Interleukin-13: A pivotal target against influenza-induced exacerbation of chronic lung diseases

Non-communicable, chronic respiratory diseases (CRDs) affect millions of individuals worldwide. The course these CRDs (asthma, obstructive pulmonary disease, and cystic fibrosis) are often punctuated by microbial infections that may result in hospitalization associated with increased risk morbidity mortality, as well reduced quality life. Interleukin-13 (IL-13) is a key protein regulates airway inflammation mucus hypersecretion. There has been much interest IL-13 from the last two decades. This cytokine believed to play decisive role exacerbation during viral infections, especially, those pre-existing CRDs. Here, we discuss common CRDs, potential plays virus-induced disease pathogenesis We also discuss, detail, immune-modulation could be translated in-depth studies develop IL-13-based therapeutic entities.